Simultaneous signal optimization of refraction and attenuation in x-ray grating interferometry: A case study for breast imaging.

ABSTRACT:

Background

X-ray grating interferometry has emerged as a promising imaging technique for breast computed tomography (BCT), offering complementary contrast from refraction beyond conventional absorption imaging. Although it provides higher resolution, the required dose levels remain above those typically used for breast cancer diagnostic imaging.

Purpose

This study aims to design an optimized grating interferometry-based BCT system using a novel optimization metric that simultaneously maximizes signal strength from refraction and attenuation while considering grating fabrication and system constraints.

Methods

A systematic grid search was conducted to identify system configurations that optimize contrast-to-noise ratio while accounting for dose efficiency in both atten

SUBMITTER: Pereira A 

PROVIDER: S-EPMC12509792 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature