Solid-state fermented Artemisia argyi residue improves immune response and intestinal integrity of broilers challenged with Clostridium perfringens.

ABSTRACT: Necrotic enteritis (NE) caused by Clostridium perfringens (C. perfringens) in broilers is rising with antibiotic restrictions, severely undermining their health and productivity, and necessitating safe, effective alternatives for control. Artemisia argyi is rich in bioactive compounds, and fermented herbal medicines confer multiple benefits for animal health. However, the potential of solid-state fermented Artemisia argyi residues (AARF) for controlling NE remains underexplored. This study aimed to verify the hypothesis that AARF improves immune responses and intestinal integrity in broilers challenged with C. perfringens. Broilers were assigned into five groups: an uninfected control (Con) group, an infected control (CP) without AARF group, and three infected groups treated with AARF at 1

SUBMITTER: Xue F 

PROVIDER: S-EPMC12510000 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature