Causal association between sleep duration, daytime napping, sleep disorders and ischemic heart disease: A systematic review and meta‑analysis of Mendelian randomization studies.

ABSTRACT: Ischemic heart disease (IHD) is a disease with high mortality and disability. Numerous studies have established a significant correlation between IHD and sleep. This study aims to evaluate the quality of existing Mendelian randomization (MR) studies and integrate the results to provide an overview of the latest evidence on the causal relationship between sleep patterns and IHD. We conducted a comprehensive search of PubMed, Embase and Web of Science to identify MR studies related to IHD and sleep. Studies from database inception to September 9, 2024 were included. Following data extraction, we performed a rigorous quality evaluation and meta-analysis. Quality assessment was conducted through the Strengthening the Reporting of Observational Studies in Epidemiology using Mendelian Ran

SUBMITTER: Shen YN 

PROVIDER: S-EPMC12510016 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature