The Connection Between Cognitive and Cardiac Function Following Kidney Transplant: The VINTAGE Study.

ABSTRACT:

Rationale & objective

The effects of successful kidney transplant (KT) on cognitive function remain unclear. To clarify how the presence or absence of pre-KT mild cognitive impairment (MCI) affects cognitive changes (overall and domain) after KT. To determine whether the cognitive improvement after KT is associated with improved cardiac function.

Study design

A hybrid retrospective and prospective observational cohort study.

Setting & participants

We obtained data from 70 recipients who underwent living donor KT (2017-2021).

Predictors

Pre-KT MCI status and left ventricular (LV) remodeling.

Outcomes

Changes in mean Montreal cognitive assessment (MoCA) scores before and after KT.

Statistical analysis

We evaluated whether the presence or absence of

SUBMITTER: Hidaka S 

PROVIDER: S-EPMC12510026 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature