Mapping and ablation outcomes of extra-pulmonary vein triggers in atrial fibrillation: single-centre retrospective study with consistent provocation protocol.

ABSTRACT:

Aims

Extra-pulmonary vein triggers (ExPVTs) are recognized as important contributors to atrial fibrillation (AF) recurrence after radio-frequency catheter ablation (RFCA). This study aimed to investigate the clinical characteristics, diagnostic value, and prognostic implications of isoproterenol-induced ExPVTs in patients undergoing de novo RFCA with circumferential pulmonary vein isolation (CPVI).

Methods and results

We analysed 2619 non-valvular AF patients (25.8% female, mean age 59.4 ± 10.9 years, 60.7% with paroxysmal AF) who underwent CPVI and standardized isoproterenol provocation testing; 98.2% also received empirical right atrial (RA) ablation. We evaluated the clinical and prognostic significance of ExPVTs for AF recurrence within 2 years, considering their anatomi

SUBMITTER: Cho S 

PROVIDER: S-EPMC12510313 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature