The choroid plexus water density.

ABSTRACT:

Purpose

To quantify normative ranges and circadian variability of the choroid plexus (ChP) water density in healthy adults.

Methods

Actigraphy assessments of circadian activity were performed for 5 days in healthy participants (n = 15; age = 28.5 ± 6.5 years) and subsequently participants underwent repeated, high spatial resolution proton density-weighted imaging (spatial resolution = 0.25 × 0.25 × 1.50 mm) with a driven equilibrium (DRIVE) module at 3 T across four time epochs during wakefulness: 7:00 to 9:00, 11:00 to 13:00, 16:00 to 18:00, and 19:00 to 21:00. ChP water density (unitless ratio of mL water/mL ChP) was calculated as the product of white matter water density and the ratio of the ChP and white matter signal intensity at the level of the atria of the lateral ve

SUBMITTER: Dubois AR 

PROVIDER: S-EPMC12510407 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature