Comparative study of Japanese nationwide epidemiological studies of myasthenia gravis using datasets of 2006 and 2018.

ABSTRACT:

Objective

This study aimed to identify changes in the clinical presentation and treatment patterns of myasthenia gravis (MG) in Japan by comparing data from nationwide epidemiological surveys conducted in 2006 and 2018.

Methods

We analyzed data from nationwide epidemiological surveys of MG performed across Japan in 2006 (n = 729) and 2018 (n = 1,357). Both surveys adhered to the Survey Manual of Study on Continuous Epidemiological Data Collection of Intractable Diseases established by the Ministry of Health, Labour, and Welfare. We compared the following variables between the two-time points: age of onset, gender distribution, initial symptoms, anti-acetylcholine receptor antibody (AChRAb) status, physiological test results (repetitive nerve stimulation test, edrophonium tes

SUBMITTER: Yoshikawa H 

PROVIDER: S-EPMC12510604 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature