Updated meta-analysis of fractional flow reserve versus coronary angiography for guiding percutaneous coronary intervention.

ABSTRACT:

Background

Fractional Flow Reserve (FFR) has been widely utilized in clinical practice for decades,however, the comparative clinical outcomes of FFR-guided versus coronary angiography (CAG)-guided percutaneous coronary intervention (PCI) still warrant further evaluation.

Methods and materials

Randomized controlled trials (RCTs) comparing FFR-guided and CAG-guided PCI were systematically searched in PubMed, Embase and the Cochrane library databases from their respective inception to December 31, 2023. Primary endpoints included the incidence of major adverse cardiovascular events (MACE), all cause mortality, myocardial infarction (MI) and target vessel revascularization(TVR). Stratified analyses were performed to evaluate the effects of FFR-guided versus CAG-guided PCI across

SUBMITTER: Yin F 

PROVIDER: S-EPMC12510650 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature