Targeted nanosponge-based treatment for pulmonary hypertension: A novel approach.

ABSTRACT: Pulmonary Hypertension (PH) is a progressive and potentially fatal condition marked by high pulmonary artery pressure, resulting in heart failure and reduced oxygenation. Despite advancements in treatments, therapeutic options for PH remain limited, particularly in cases resistant to conventional therapies. In biomedical research, nanotechnology has become a potential area of study, presenting novel approaches to drug delivery and tissue targeting. Nanosponges, a class of nanoparticles with porous structures, have gained attention for their ability to encapsulate therapeutic agents, enhance drug stability, and provide controlled release. Nanosponges can be engineered to deliver vasodilators, anti-inflammatory drugs, and gene therapies directly to the pulmonary vasculature, minimizing syste

SUBMITTER: Kaur J 

PROVIDER: S-EPMC12510689 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature