Poor olfaction and risk of heart failure in the Atherosclerosis Risk in Communities Study.

ABSTRACT:

Background

Poor olfaction may be associated with incident heart failure (HF) in older adults, but empirical evidence is scant.

Methods

We included 5217 participants free of clinical HF and with a smell assessment in 2011-2013 from the Atherosclerosis Risk in Communities Study. Olfaction was measured by the 12-item Sniffin' Sticks odor identification test and defined as good (score 11-12), moderate (9-10), or poor (≤8). Participants were followed until the first HF hospitalization, death, last contact, or December 31, 2020, whichever happened first. We estimated adjusted risk ratios (aRR) for associations of olfaction with incident HF and its subtypes, and cross-sectional associations of olfaction with subclinical HF markers, including N-terminal pro-B-type natriuretic peptid

SUBMITTER: Chamberlin KW 

PROVIDER: S-EPMC12510733 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature