Alkaline phosphatase predicts short-term postoperative outcome in adult patients with moyamoya disease.

ABSTRACT:

Background

Alkaline phosphatase (ALP) has played a pivotal role in vascular diseases in recent years. However, the association between ALP level and postoperative complications of moyamoya disease (MMD) has not been studied.

Patients and methods

Blood samples were collected from recruited patients with MMD. The serum ALP concentrations of the patients were determined using non-frozen specimens via an automated enzymatic assay. Patients were then divided into two groups according to the median, and a comparative analysis was performed. Patients were stratified into two cohorts for statistical evaluation based on the occurrence of postoperative stroke events. We employed a nomogram to identify risk factors for postoperative events. We also created a Cox model to analyze the ri

SUBMITTER: Sun W 

PROVIDER: S-EPMC12510858 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature