The role of exercise induced capillarization adaptations in skeletal muscle aging: a systematic review.

ABSTRACT:

Background

Skeletal muscle aging is often accompanied by capillary rarefaction, which limits the effective delivery and distribution of hormones, nutrients, and growth factors within skeletal muscle. Furthermore, exercise is widely regarded as having the potential to improve microcirculation and delay skeletal muscle aging. This review aims to explore exercise-induced improvements in capillarization and related adaptations to mitigate the adverse changes that occur during the aging process of skeletal muscle.

Methods

This systematic review was conducted in accordance with the PRISMA guidelines and registered in the PROSPERO database under the identifier CRD420251055873. Studies involving exercise interventions in older adults were included, with the requirement that at least

SUBMITTER: Ding Y 

PROVIDER: S-EPMC12510980 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature