Postoperative Complications of Single-Level Lumbar Spine Fusion in Patients With Preoperative Vitamin D Deficiency: A Retrospective Cohort Study.

ABSTRACT: Study DesignRetrospective cohort study.ObjectivesTo assess whether preoperative vitamin D deficiency is associated with increased postoperative complications after single-level lumbar fusion.MethodsWe queried a national EHR network for adults undergoing posterior/posterolateral single-level lumbar fusion. Vitamin D deficiency was defined by the most recent preoperative 25-hydroxyvitamin D <20 ng/mL. Patients with multilevel fusion, <2-year follow-up, scoliosis, or spinal cord neoplasm were excluded. Propensity-score matching (1:1) on demographics, Charlson Comorbidity Index, obesity, osteoporosis, nicotine dependence, vitamin D supplementation, celiac disease, inflammatory bowel disease, chronic pancreatitis, and cystic fibrosis yielded 1365 patients per cohort (from 1372 deficient and 89,

SUBMITTER: Garcia D 

PROVIDER: S-EPMC12510990 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature