Complete resection of brain metastases - when does it matter?

ABSTRACT:

Purpose

The value of gross total resection (GTR) in patients with brain metastases (BM) is controversial. Therefore, we analyzed the circumstances under which GTR is crucial for optimal outcome in a large population of patients with BM treated with surgical resection at our institution.

Methods

The analysis included 539 patients. The extent of resection was rated as complete if no residual contrast-enhancing tumor was detectable on the early postoperative magnet-resonance image (MRI); the tumor size was determined by measuring the volume of the contrast-enhancing areas on the presurgical MRI. Outcome included overall survival (OS) and progression-free survival (PFS).

Results

GTR was achieved in most patients (82.8%) but was not associated with longer OS and PFS in the

SUBMITTER: Araceli T 

PROVIDER: S-EPMC12511165 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature