Unveiling regional differences in glioblastoma patient survival with real-world data from the Norwegian brain tumor quality registry.

ABSTRACT:

Purpose

Surveillance of patient outcomes with real-world data is essential to uncover regional disparities in clinical practice or quality of care. This study explored survival differences among glioblastoma patients in Norway and investigated the role of demographic and treatment factors.

Methods

We analyzed real-world data from the Norwegian Cancer Registry on 1158 adults with histologically confirmed glioblastoma during 2019-2023. Surgical treatment rates per 100,000 inhabitants per region (South-East, West, Mid, North) were compared using adjusted Poisson models. Full treatment included surgical resection, radiotherapy (≥ 55 Gy for ≤ 70 years; ≥30 Gy for > 70 years), and temozolomide. Standardized survival was estimated with flexible parametric models, standardized for a

SUBMITTER: Trewin-Nybraten CB 

PROVIDER: S-EPMC12511213 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature