Fermented Soybean Pulp Alleviates Disease Progression of 5×FAD Model Mice.

ABSTRACT: Alzheimer's disease (AD) is the most common neurodegenerative disorder of the central nervous system, characterized by memory loss and cognitive decline. The two main hypotheses regarding AD involve the accumulation of amyloid-β (Aβ) forming plaques and the intracellular hyperphosphorylation of tau protein, leading to the formation of neurofibrillary tangles (NFT). These processes are accompanied by neuroinflammation and oxidative stress, and eventual neuronal death. While soy foods are widely recognized for their nutritional benefits, soybean pulp (okara), the residue left over from making tofu or soybean milk, is mostly discarded as kitchen waste, despite being rich in nutrients such as dietary fiber, protein, and isoflavones. This underutilized byproduct may serve as a valuable resource

SUBMITTER: Yang CY 

PROVIDER: S-EPMC12511221 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature