Genetic evaluation of sudden unexpected death in infants and children.

ABSTRACT: The Dutch Postmortem Evaluation of Sudden Unexpected Death in Infants and Children (PESUDIC) procedure investigates cases of sudden unexpected death in infants and children (SUDI and SUDC). These deaths may have a genetic basis. This national retrospective study examined the yield of genetic testing in PESUDIC cases to provide recommendations for genetic evaluation of SUDI and SUDC. Children who underwent the PESUDIC procedure from 2016 to 2022 and had genetic testing performed were included. They were categorized into three groups: (A) cases where standard PESUDIC investigations yielded contributive findings; (B) cases with no contributive findings from standard investigations, but with comorbidities present; (C) cases without contributive findings from standard investigations or comorbid

SUBMITTER: Pries AM 

PROVIDER: S-EPMC12511225 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature