Diagnostic multiparametric models and antibiotic practices in febrile infants younger than 90 days.

ABSTRACT: Most studies in febrile infants evaluated individual laboratory data to predict diagnoses of febrile infants, not taking into consideration the combination of data. In this study we aimed to analyze the diagnostic accuracy - both individually and in combination - of C-reactive protein (CRP), procalcitonin (PCT), white blood cell count (WBC), and neutrophil count (ANC), along with clinical findings, in predicting whether a young febrile infant has a viral infection, urinary tract infection (UTI) or serious bacterial infection (SBI). This is a retrospective, observational, single center, cohort study during a period of 7 years (2018-2024). A total of 615 patients were included in the study, of which 352 male (57.3%) with a median age of 51 days (IQR). For the detection of SBI, AUC values wer

SUBMITTER: Martino L 

PROVIDER: S-EPMC12511232 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature