Nasopharyngeal and oral microbiota profiling in SARS-CoV-2 infected pregnant women.

ABSTRACT: Variations have been found in the upper respiratory tract microbiota in SARS-CoV-2 positive patients compared to healthy subjects, with different dominant species and diversity indexes detected, including a decrease in biodiversity and an increased abundance of bacterial pathogens. Moreover, these discrepancies were observed in patients with both mild and severe symptoms. Notably, the inflammatory state appears to be significantly influenced by the characteristics of the indigenous microbiota. This is particularly interesting in pregnant patients, as pregnancy involves an adaptive adjustment of the microbiota due to hormonal changes aimed at providing immune protection. The relationship between the microbiota of pregnant women and SARS-CoV-2 has not been deeply explored so far. The purpose

SUBMITTER: Giovannini N 

PROVIDER: S-EPMC12511543 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature