Environmental risk factors of neuromyelitis optica spectrum disorder: a systematic review.

ABSTRACT:

Background

Neuromyelitis optica spectrum disorder (NMOSD) may be triggered by environmental risk factors.

Objectives

We aimed to explore and integrate the recent research advances in this field. Here we describe relevant studies and summarize current knowledge on non-genetic factors that influence the onset of the disease.

Design

Systematic review.

Methods

We performed a systematic review up to May 21, 2024, following preferred reporting items for systematic reviews and meta-analyses guidelines. Two independent reviewers evaluated the quality of the included studies using the Joanna Briggs Institute checklist for risk of bias assessment.

Data sources

MEDLINE, EMBASE, Scopus, and Web of Science databases.

Results

A total of 15,869 articles were eva

SUBMITTER: Mohammadi Lapevandani M 

PROVIDER: S-EPMC12511702 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature