Indications and recent evidence for apheresis in children and adults with kidney diseases: a comprehensive review.

ABSTRACT:

Introduction

Plasmapheresis has been a therapeutic option in kidney diseases to eliminate disease-causing autoantibodies, circulating factors, and abnormal components involved in complement pathways. We aim to systematically review the effectiveness and adverse events associated with plasmapheresis and related apheresis therapies in treating kidney diseases in paediatric and adult populations.

Methods

We searched databases including EMBASE, CINAHL, PubMed, and Cochrane Central for studies from 2010 to October 2023. The search terms included terms related to glomerulonephritis treated with plasmapheresis. Outcomes included the patient's length of hospital stay, mortality, development of kidney failure, associated comorbidities, and adverse events. Risk of bias was assessed us

SUBMITTER: Raina R 

PROVIDER: S-EPMC12511939 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature