Isolation and genetic characterization of parvovirus from Bengal tiger in China.

ABSTRACT:

Background

Canine parvovirus (CPV) poses an emerging threat to endangered felids, yet its epidemiology and evolutionary dynamics in tigers remain poorly characterized.

Methods

Pathogen detection was performed through necropsy, colloidal gold assays, and PCR on a deceased Bengal tiger, followed by genetic and molecular characterization of the identified CPV.

Results

This study isolated a CPV-2c strain (HNSY-031) from captive Bengal tigers. Genetic analysis revealed its closest relationship to Vietnamese canine parvoviruses, with 100% identity to CPV strains circulating in China and Vietnam since 2020. Molecular characterization identified 12 amino acid mutations within the VP2 protein, including key residues associated with host adaptation and viral evolution.

Concl

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12512266 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature