Endovascular Thrombectomy Versus Medical Therapy Alone in Patients With Large Core Based on Computed Tomography Perfusion.

ABSTRACT:

Background

Patients presenting with large vessel occlusion and a large ischemic core (>50 mL) have been consistently undersampled in the major endovascular thrombectomy (ET) trials. As such, equipoise exists as to whether ET is associated with improved outcomes over medical therapy alone in this population.

Methods

Prospectively collected databases from 4 US centers were reviewed to identify patients with baseline ischemic cores >50 mL based on computed tomography perfusion imaging using RAPID software (iSchemaView), who were treated with ET or medical therapy alone between January 2014 and October 2019. Baseline characteristics, procedural information, and clinical follow-up data were collected. A matched-control comparison of these patients was performed.

Results

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SUBMITTER: Aghaebrahim AN 

PROVIDER: S-EPMC12512350 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature