Early oral feeding after laparoscopic total gastrectomy in gastric cancer patients: a meta-analysis of randomized controlled trials and cohort studies.

ABSTRACT:

Background

Gastric cancer remains a leading cause of cancer-related morbidity and mortality worldwide, with surgery being central to treatment. However, postoperative malnutrition is common and significantly impairs recovery. Early oral feeding (EOF) has been proposed as a strategy to promote gastrointestinal recovery and reduce complications, but its clinical effectiveness following gastrectomy remains uncertain.

Methods

A systematic review and meta-analysis were conducted according to PRISMA guidelines. Studies comparing EOF with delayed oral feeding (TOF) in gastric cancer patients were included. Outcomes assessed were hospital stay, time to first anal exhaust, postoperative complications, feeding tolerance, and serum albumin and prealbumin levels. Data were pooled using

SUBMITTER: Mohajeri L 

PROVIDER: S-EPMC12512641 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature