Evaluation of a screening and isolation strategy to curb carbapenem-resistant gram-negative bacteria in Hanoi, Vietnam: a pragmatic before-after study.

ABSTRACT:

Background

Carbapenem resistance among gram-negative bacilli is a major threat worldwide, particularly in Vietnam. The study aimed to evaluate the magnitude of carbapenem resistance in gram-negative bacilli in intensive care units (ICU) in Vietnam and evaluate the impact of a screening and isolation strategy on their epidemiology.

Methods

A before-after study was performed where patients were screened for digestive carriage of carbapenem-resistant and carbapenemase-producing gram-negative (CRGN) bacilli at ICU admission and weekly thereafter during a reference period and an intervention period. The intervention consisted of the implementation of isolation precautions for carriers throughout their ICU hospitalization.

Results

The proportion of CRGN digestive carriers a

SUBMITTER: Toan NQ 

PROVIDER: S-EPMC12512652 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature