Superselective transarterial chemoembolization (SSTACE) as second-line conversion therapy for locally advanced unresectable gastric or gastroesophageal junction adenocarcinoma: a preliminary retrospective cohort study.

ABSTRACT:

Background

In patients with locally advanced unresectable gastric or gastroesophageal junction adenocarcinoma, conversion therapy has shown suboptimal efficacy, typically resulting in stable disease (SD) or progressive disease (PD) leading to low surgical conversion rates and unfavorable prognosis. This study seeks to assess the efficacy and safety of superselective transarterial chemoembolization (SSTACE) in treating this specific patient cohort.

Methods

This retrospective cohort study analyzed patients diagnosed with locally advanced unresectable gastric cancer (GC) or gastroesophageal junction (GEJ) adenocarcinoma at the Affiliated Hospital of North Sichuan Medical College between January 2019 and March 2025. All of them underwent a single session of SSTACE, followed by a

SUBMITTER: Chen J 

PROVIDER: S-EPMC12512653 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature