The genetic influence of sex on gene expression for blood in pigs.

ABSTRACT:

Background

Pigs are one of the most important farm animals in the agrifood industry. Many complex traits and patterns of gene expression exhibit sexual dimorphisms in pigs. However, the impact of sex on gene expression remains poorly understood.

Results

In this study, we utilized the gene expression data of blood tissue derived from PigGTEx project to explore the genetic influence of sex on gene expression in pigs. Differential gene expression analysis identified 116 male-biased and 248 female-biased genes. Sex-combined and sex-stratified cis-heritability (cis-h²) were highly positively correlated, while the low correlation were observed between male-stratified and female-stratified cis-h². Sex-interaction expression quantitative trait locus (eQTL) mapp

SUBMITTER: Lin Q 

PROVIDER: S-EPMC12512681 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature