β-caryophyllene regulates H3K36me3 to inhibit conidial germination and mycelial growth of Fusarium proliferatum.

ABSTRACT:

Background

Panax notoginseng is a valuable traditional Chinese medicine and is highly susceptible to root rot disease, which is primarily caused by the pathogenic fungus Fusarium proliferatum. The antifungal mechanisms underlying the effects of β-caryophyllene (BCP), which is commonly found in Essential oils (EOs), remain unclear. In this study, RNA sequencing (RNA-seq) and chromatin immunoprecipitation sequencing (ChIP-seq), along with in vitro antifungal experiments, were used to investigate the inhibitory effects of BCP on F. proliferatum.

Results

BCP not only influenced the mycelial growth of F. proliferatum but also exerted a pronounced inhibitory effect on conidial germination. After treatment with 200 mM BCP, the inhibition rate of mycelial growth was 24.5%, whereas t

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12512827 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature