Prognostic value of the pretreatment Naples prognostic score in gastrointestinal cancer patients: an updated meta-analysis with 28 studies.

ABSTRACT:

Background

The Naples prognostic score (NPS) has been extensively documented as a promising prognostic biomarker in various malignancies. The objective of this study is to systematically investigate the correlation between the pretreatment NPS and survival outcomes in patients with gastrointestinal (GI) cancer.

Methods

This meta-analysis was prospectively registered with PROSPERO (CRD42024567576). We conducted a systematic literature search using electronic databases, including Web of Science, PubMed, and Embase, from inception until July 1st, 2024. The primary endpoints assessed were long-term survival outcomes. Pooled hazard ratios (HR) with corresponding 95% confidence intervals (CI) were calculated using a random-effects model during the pooled analysis. Additionally, pr

SUBMITTER: Pang H 

PROVIDER: S-EPMC12512894 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature