Effect of immediate kangaroo mother care (iKMC) on neonatal mortality and culture-positive sepsis in low-birth-weight neonates in district hospitals in Chhattisgarh, India (PRISM study): protocol for a stepped-wedge cluster randomized trial.

ABSTRACT:

Background

The high rates of culture-positive sepsis, sepsis-related mortality, and multidrug resistance in neonates admitted to special care newborn units in district hospitals (DH) in India necessitate urgent actions to prevent infections in these settings. Immediate kangaroo mother care (iKMC), initiated before stabilization within the first few hours of life, has been shown to reduce neonatal mortality among low birth weight (LBW) neonates admitted to tertiary care hospitals. However, the effect of iKMC on sepsis and sepsis-related mortality, particularly in DH, remains unclear. This study aims to evaluate whether iKMC can lower the incidence of mortality or culture-positive sepsis in LBW neonates admitted to neonatal units in district hospitals.

Methods

This stepped-wed

SUBMITTER: Prakash S 

PROVIDER: S-EPMC12512956 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature