Global prevalence of metabolic syndrome in patients with Rheumatoid arthritis: a systematic review and meta-analysis.

ABSTRACT:

Background

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that increases the risk of systemic complications, particularly metabolic syndrome (MetS). MetS, defined by central obesity, hypertension, hyperglycemia, and dyslipidemia, not only raises cardiovascular risk but also worsens the prognosis of RA. This meta-analysis aimed to estimate the global prevalence of MetS in RA patients and identify clinical factors contributing to its occurrence.

Methods

A comprehensive literature search was conducted in PubMed, Scopus, and Web of Science. Studies included in the analysis diagnosed RA and defined MetS using standardized guidelines. Pooled estimates were calculated using a random-effects model. Heterogeneity was assessed using the I² statistic. All statistical analys

SUBMITTER: Jafari M 

PROVIDER: S-EPMC12513099 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature