Cerebral small vessel disease lesion segmentation methods: A systematic review.

ABSTRACT: Cerebral small vessel disease (CSVD) can manifest as brain lesions visible on magnetic resonance imaging, including white matter hyperintensities (WMH), cerebral microbleeds (CMB), perivascular spaces (PVS), lacunes, and recent small subcortical infarcts (RSSI). Detection and segmentation of these imaging markers can provide valuable information on brain health, including prevention and treatment of dementia. However, manual segmentation is cumbersome, especially for large cohorts in research studies. There has been extensive research into the development of automated tools using machine learning to increase accuracy and efficiency in lesion segmentation. This systematic review aimed to summarize novel automated methods developed over the last 10 years that segment CSVD lesion types and ha

SUBMITTER: Phelps J 

PROVIDER: S-EPMC12513155 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature