Herring oil rich in long-chain monounsaturated fatty acid (C22: 1n-11) lowers plasma lipids and modulates fatty acid composition, oxidation, and inflammation in rats.

ABSTRACT:

Introduction

Marine oils and fatty fish rich in long-chain n-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (C20:5n-3, EPA) and docosahexaenoic acid (C22:6n-3, DHA), have been reported to enhance fatty acid (FA) oxidation and reduce plasma triacylglycerol and cholesterol levels. In addition to n-3 PUFAs, herring oil contains long-chain monounsaturated fatty acids (MUFAs), including cetoleic acid (C22:1n-11). This study aimed to investigate the effect of consuming CETO3^® oil-derived from herring and naturally rich in n-3 PUFAs and cetoleic acid-on plasma lipid levels, FA composition, mitochondrial oxidation, and inflammation in rats.

Methods

Rats were fed low-fat diets supplemented with 5% CETO3^® oil (experimental) or soy oil (contr

SUBMITTER: Nundal CH 

PROVIDER: S-EPMC12513201 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature