Severe dengue in adults: Clinical features from the 2022 dengue outbreak at a Vietnamese tertiary hospital.

ABSTRACT:

Background

In Vietnam, dengue has been endemic for many years, with most cases reported in children. Recently, epidemiological data show an increasing frequency in adults, especially for severe dengue. An unprecedented post-COVID-19 surge resulted in an exceptionally high number of hospitalized dengue cases. We aim to describe the clinical phenotypes and outcomes in Vietnamese adults with severe dengue during the 2022 outbreak and explore host-related factors associated with disease variability and severity, through a retrospective study.

Findings

A total of 891 cases were included, with mean age 29 ± 10 years. 284/891 (31.9%) patients had a BMI ≥ 25 kg/m2, and 240/891 (26.9%) had comorbidities. The predominant severe clinical phenotype was dengue shock syndrome (DSS): 737/8

SUBMITTER: Pham OK 

PROVIDER: S-EPMC12513615 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature