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Mapping the distribution of Nipah virus infections: a geospatial modelling analysis.


ABSTRACT:

Background

Nipah virus is a zoonotic paramyxovirus responsible for disease outbreaks with high fatality rates in south and southeast Asia. However, knowledge of the potential geographical extent and risk patterns of the virus is poor. We aimed to establish an integrated spatiotemporal and phylogenetic database of Nipah virus infections in humans and animals across south and southeast Asia.

Methods

In this geospatial modelling analysis, we developed an integrated database containing information on the distribution of Nipah virus infections in humans and animals from 1998 to 2021. We conducted phylodynamic analysis to examine the evolution and migration pathways of the virus and meta-analyses to estimate the adjusted case-fatality rate. We used two boosted regression tree mode

SUBMITTER: Sun YQ 

PROVIDER: S-EPMC12513742 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature