Early radiologic tumour volume response in non-metastatic rhabdomyosarcoma is not predictive for survival.

ABSTRACT:

Background

There is an urgent need for early radiological markers predicting survival in paediatric rhabdomyosarcoma patients.

Objective

To analyse the predictive value of early radiological tumour volume response to chemotherapy in non-metastatic rhabdomyosarcoma patients.

Methods

The European paediatric Soft tissue sarcoma Study Group (EpSSG) RMS 2005 study prospectively included non-metastatic rhabdomyosarcoma patients. Patients with Intergroup Rhabdomyosarcoma Studies (IRS) postsurgical Group III (i.e. measurable disease) at diagnosis, with three tumour diameters available at diagnosis and following three cycles of chemotherapy, were included. Tumour response was categorized as complete response, partial response, minor partial response, stable disease, or progres

SUBMITTER: de Vries ISA 

PROVIDER: S-EPMC12513956 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature