Biometry and volumetry in multi-centric fetal brain magnetic resonance imaging: assessing the bias of super-resolution reconstruction.

ABSTRACT:

Background

Fetal brain MRI is increasingly used to complement ultrasound imaging. Images are processed using complex super-resolution reconstruction pipelines, which may bias biometric and volumetric measurements.

Objective

To assess the consistency of 2-dimensional (D) biometric and 3-D volumetric measurements across three hospitals using three widely used super-resolution reconstruction pipelines.

Materials and methods

This retrospective multi-centric study used T2-weighted fetal brain MRI scans acquired at three hospitals between 2009 and 2023. MRIs from each subject were reconstructed with each super-resolution reconstruction method, and biometric measurements were performed by four experts. Automated 3-D volumetry was performed using a state-of-the-art segmentati

SUBMITTER: Sanchez T 

PROVIDER: S-EPMC12513972 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature