The role of biogenic aluminium oxide nanoparticles (Al₂O₃ NPs) synthesised from Solanum virginianum L in combating microbial vaginal pathogens.

ABSTRACT: Microbial vaginosis results from an elevation in biofilm-forming vaginal bacteria. They provide a considerable clinical concern due to the rising global antibiotic resistance. This work investigated the antibacterial and anti-biofilm characteristics of Al₂O₃ NPs synthesised from Solanum virginianum L. Fourier. The characterisation techniques Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Ultraviolet-visible spectroscopy (UV-Vis), and Energy-dispersive X-ray spectroscopy (EDX) validated the synthesis and structural integrity of the nanoparticles. Marked antibacterial and antifungal efficacy was noted against 108 isolates of various microorganisms (G. vaginalis, S. aureus, E. coli, P. aeruginosa, and C. albicans). Al₂O₃ displayed

SUBMITTER: Zubair M 

PROVIDER: S-EPMC12514175 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature