Association of magnesium sulphate use with mortality in patients with acute respiratory distress syndrome: a retrospective propensity score-matched cohort study.

ABSTRACT: Few reports have documented magnesium supplementation effects on mortality rates of patients with acute respiratory distress syndrome (ARDS). This study investigated the potential correlation between magnesium sulphate use and mortality in patients with ARDS. Records of critically ill adult patients with ARDS from the Medical Information Mart in Intensive Care IV database were analysed. The exposure was magnesium sulphate administration during intensive care unit (ICU) stay. The primary outcome was in-hospital mortality. A 1:1 ratio propensity score matching (PSM) was performed; multivariable analyses were conducted to account for potential confounders. The study cohort comprised 5,499 patients before PSM and 1,282 patients after PSM. For PSM, the in-hospital mortality rates were 32.29% (2

SUBMITTER: Cao YF 

PROVIDER: S-EPMC12514253 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature