Analysis of preoperative predictors for pouchitis after surgery for ulcerative colitis: A multicentre retrospective study of the clinical outcome of surgery for ulcerative colitis in Japan (COSUC study).

ABSTRACT:

Background

Pouchitis is a prevalent complication following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) and significantly impacts patient outcomes. The identification of risk factors and development of predictive models would help to guide perioperative management.

Methods

This multicentre retrospective study analysed data from 1136 UC patients who underwent IPAA between 2005 and 2019 as part of the Clinical Outcome of Surgery for Ulcerative Colitis (COSUC) study. Potential risk factors, including demographic, clinical and surgical variables, were assessed using univariable and multivariable logistic regression. A predictive model was developed and validated using separate cohorts, with performance evaluated via receiver operating characteristic (ROC) curv

SUBMITTER: Kasashima H 

PROVIDER: S-EPMC12514329 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature