Clinical and cost-effectiveness of eye movement desensitization and reprocessing for treatment and prevention of post-traumatic stress disorder in adults: A systematic review and meta-analysis.

ABSTRACT: The objective was to provide up-to-date clinical and cost-effectiveness evidence investigating eye movement desensitization and reprocessing (EMDR) for treatment or prevention of adult post-traumatic stress disorder (PTSD). We conducted a systematic review of randomized controlled trials (RCTs) and cost-effectiveness studies assessing PTSD symptoms in adults, published since the NICE 2018 guidelines. EMDR was compared with trauma-focused-cognitive behavioural therapy (TF-CBT), waitlist or usual care. Six databases were searched in September 2023. Risk of bias was assessed. Data synthesis included Bayesian meta-analyses of standardized mean differences if sufficient data were available from at least three RCTs. From 2038 records, 17 studies met the eligibility criteria. One modelling-based

SUBMITTER: Simpson E 

PROVIDER: S-EPMC12514334 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature