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ABSTRACT: Objective
To: (a) interrogate the concept of general mental ability reflected by "Spearman's g" factor in participants with Juvenile Myoclonic Epilepsy (JME) and control participants; (b) understand g's clinical, familial, socioeconomic, and brain structural correlates; and (c) determine g's relationship with variable cognitive pathology in JME and the neuroanatomical correlates of association.Methods
Seventy-seven JME and 43 typically developing unrelated control participants (mean ages 19.7 and 20.3 years, respectively) were administered a comprehensive neuropsychological battery with characterization of clinical epilepsy and familial features, determination of socioeconomic status, and structural neuroimaging. g was estimated through factor analysis and compared between
SUBMITTER: Struck AF
PROVIDER: S-EPMC12514386 | biostudies-literature | 2025 Oct
REPOSITORIES: biostudies-literature