Proactive antimicrobial stewardship with real-time microbiological alerts improves management of bloodstream infections.

ABSTRACT:

Introduction

This study aims to assess the impact of proactive Infectious Disease Specialist (IDS) interventions, in addition to standard antimicrobial stewardship (AMS) practices, triggered by real-time microbiological alerts, on improving the appropriateness and timeliness of antimicrobial prescriptions in hospitalized patients with bloodstream infections (BSIs).

Methods

We conducted a prospective, single-center, pre-post interventional study at the University Hospital of Modena, Italy. Adult inpatients with monomicrobial BSIs between June 2022 and March 2023 were included. During the intervention phase (November 2022-March 2023), real-time microbiological alerts were automatically delivered to IDS consultants, who proactively reviewed therapy. Primary outcomes included th

SUBMITTER: Di Marcello A 

PROVIDER: S-EPMC12514464 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature