Incidence and outcomes of anal and cervical cancer among adults with HIV in Latin America: a retrospective cohort study.

ABSTRACT:

Introduction

Human papillomavirus (HPV)-associated cervical and anal cancers disproportionately affect people with HIV (PWH). This study aimed to determine the incidence trends of and risk factors for these malignancies in PWH in Latin America.

Methods

We included PWH from the Caribbean, Central and South America network for HIV epidemiology (CCASAnet) who contributed person-time between 2000 and 2019. We calculated crude and age-standardized incidence rates, examining trends over time with Poisson regression. Adjusted hazard ratios were calculated using Cox proportional hazard models with propensity score adjustment. We calculated the probability of survival after cancer diagnosis using Kaplan-Meier curves. To understand factors that influence our results, we surveyed all a

SUBMITTER: Pellegrino RA 

PROVIDER: S-EPMC12514557 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature