Functional organization of the allostatic interoceptive network in adolescence: Links to peer victimization and prospective depressive symptoms.

ABSTRACT: The present study examines the role of brain network organization in the prospective prediction of adolescent depressive symptoms and links to the social and psychological context. Using a path model with data from a larger longitudinal study of adolescents beginning in 6th-8th grade (N = 117, 55 % female, M_{age at scan}= 12.99), we first established that organizational properties of brain networks theoretically linked to depression predicted greater depressive symptoms two years later. Specifically, when controlling for gender and initial depression, greater global efficiency of the allostatic interoceptive network (AIN) and greater segregation of the frontoparietal network (FPN) from the salience network (SN) predicted depressive symptoms an average of two years later. Linking t

SUBMITTER: Frye NG 

PROVIDER: S-EPMC12514570 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature