Air Purifier Intervention for Respiratory Viral Exposure in Elementary Schools: A Secondary Analysis of a Randomized Clinical Trial.

ABSTRACT:

Importance

The magnitude of school respiratory virus exposure and the effectiveness of environmental mitigation measures remain unclear.

Objective

To evaluate whether portable high-efficiency particulate air (HEPA) purifiers are associated with reduced respiratory virus exposure in elementary school classrooms.

Design, setting, and participants

This ad hoc secondary analysis was performed between July 2023 and September 2024 and used data from a cluster-randomized, placebo-controlled trial (School Inner-City Asthma Intervention Study) of HEPA purifiers conducted from September 2015 to June 2020. A total of 200 classrooms from 39 public schools in Northeastern US were enrolled and randomized.

Interventions

Classrooms were randomized 1:1 to receive either active

SUBMITTER: Sun Y 

PROVIDER: S-EPMC12514627 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature