Predicting glioma histo-molecular diagnosis and prognosis: preoperative dynamic contrast-enhanced magnetic resonance imaging insights.

ABSTRACT:

Background

The preoperative prediction of glioma, integrated histological/molecular classification, and prognosis are critical for personalized patient management and treatment optimization. This study aimed to explore whether preoperative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), an advanced MRI technique, can comprehensively and noninvasively evaluate gliomas.

Methods

Adult patients (June 2013 to May 2021) with diffuse glioma, retrospectively reclassified by the 2021 World Health Organization (WHO) classification criteria in this cohort study, underwent conventional and DCE-MRI examinations at our institution. Quantitative measurements, including the volume transfer constant (Ktrans), volume of extravascular extracellular space per unit volume of tiss

SUBMITTER: Ma H 

PROVIDER: S-EPMC12514690 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature