Predictive value of ¹⁸F-FDG PET/CT metabolic heterogeneity parameter combined with peritumoral adipose tissue abnormality and cN stage in perineural invasion of colorectal cancer: a retrospective analysis.

ABSTRACT:

Background

Colorectal cancer (CRC) is among the most prevalent malignant neoplasms within the digestive system. Perineural invasion (PNI) is a significant predictor of CRC prognosis, thus the crucial need to predict PNI status prior to surgical intervention. The aim of this study was to explore the efficacy of ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) in predicting PNI status prior to surgery in CRC patients.

Methods

This study involved the retrospective collection of ¹⁸F-FDG PET/CT data from 116 CRC patients who received treatment at our facility between January 2016 and July 2024. All patients, including 50 in the PNI group and 66 in the non-PNI group, had a surgical pathological diagnosis of

SUBMITTER: Chen Q 

PROVIDER: S-EPMC12514694 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature