Role of muscle glucometabolism derived from ¹⁸F-FDG PET/CT in sarcopenia of elderly patients with newly diagnosed malignancies.

ABSTRACT:

Background

Our previous studies have found that certain cancer patients with sarcopenia tend to present with lower glucometabolism within skeletal muscles. This study aimed to investigate the association between sarcopenia and ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) along with clinicopathological factors in elderly patients with treatment-naïve malignant tumors.

Methods

Clinicopathological and ¹⁸F-FDG PET/CT characteristics of 1,024 elderly patients with newly diagnosed malignancies [638 men, 386 women; median age: 68 years (range, 60-99 years)] were retrospectively collected. Skeletal muscle index (SMI) was calculated using skeletal muscle area (SMA) measured at the 3^rd lumbar (L3) level norma

SUBMITTER: Hu Y 

PROVIDER: S-EPMC12514704 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature