Visualizing and deciphering influenza A(H1N1) pdm09 reassortment in the 2019-23 seasons.

ABSTRACT: Influenza A viruses remain a persistent public health concern due to their extensive genomic diversity and seasonality. Among the mechanisms driving their evolution, reassortment plays a pivotal role by facilitating the exchange of gene segments between co-infecting viruses, leading to novel viral genotypes. This mechanism contributes to pandemic strains, such as the 2009 H1N1 pandemic (H1N1pdm), and affects seasonal influenza by introducing genetic changes with potential impacts on viral traits and clinical outcomes. Comprehensive reassortment analysis is therefore critical for better understanding the mechanisms underlying influenza virus evolution and their potential impact on public health. A new visualization tool, Crossing lines Annotating with Tanglegrams on Trees (CatTrees), was de

SUBMITTER: Li TJ 

PROVIDER: S-EPMC12515034 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature